Anne Dower, PhD, received her PhD in Anatomy at the Penn State College of Medicine, where her primary research interests involved investigating the role of iron regulation and metabolism in health and disease. Specifically, Dower has published work elucidating the role of a key iron regulatory protein, known as HFE, in the pathobiology of macrophages and neurodegenerative diseases. She has demonstrated her knowledge of anatomical and biomedical sciences by educating both medical and pre-medical students at both the graduate and undergraduate levels. Dower has a passion for mentoring future biomedical scientists and health professionals and explores avenues to find the best methodologies for educating her students. In her free time, Dower enjoys baking, the outdoors and spending time with her family.
Professional Society
American Association for Anatomists
Human Anatomy and Physiology Society
Selected Publications
Nixon, A. M., Meadowcroft, M. D., Neely, E. B., Snyder, A. M., Purnell, C. J., Wright, J., . . . Connor, J. R. (2018). HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity. Journal of Neurochemistry,145(4), 299-311. doi:10.1111/jnc.14299
Nixon, A. M., Neely, E., Simpson, I. A., & Connor, J. R. (2018). The role of HFE genotype in macrophage phenotype. Journal of Neuroinflammation, 15(1). doi:10.1186/s12974-018-1057-0
Nixon, A. M., & Connor, J. R. (2017). Does HFE Genotype Impact Macrophage Phenotype in Disease Process and Therapeutic Response? Biometals in Neurodegenerative Diseases, 51-66. doi:10.1016/b978-0-12-804562-6.00004-x
Adhikary, S. D., El-Boghdadly, K., Nasralah, Z., Sarwani, N., Nixon, A. M., & Chin, K. J. (2016). A radiologic and anatomic assessment of injectate spread following transmuscular quadratus lumborum block in cadavers. Anaesthesia, 72(1), 73-79. doi:10.1111/anae.13647
Connor, J. R., Zhang, X., Nixon, A. M., Webb, B., & Perno, J. R. (2015). Comparative evaluation of nephrotoxicity and management by macrophages of intravenous pharmaceutical iron formulations. PloS one, 10(5), e0125272. https://doi.org/10.1371/journal.pone.0125272
Research Interests
Iron regulation on health and disease; anatomical pedagogy