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Desai Lab Publications

Oncogenic GNAS uses PKA-dependent and independent mechanisms to induce cell proliferation in human pancreatic ductal and acinar organoids.

“Oncogenic GNAS uses PKA-dependent and independent mechanisms to induce cell proliferation in human pancreatic ductal and acinar organoids”
Ridhdhi Desai, Senthil Muthuswamy
bioRxiv. 2023 Jan 18:2023.01.16.524220. doi: 10.1101/2023.01.16.524220

Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids.

“Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids”
Huang L, Desai R, Conrad DN, Leite NC, Akshinthala D, Lim CM, Gonzalez R, Muthuswamy LB, Gartner Z, Muthuswamy SK
Cell Stem Cell. 2021 Jun 3;28(6):1090-1104.e6. doi: 10.1016/j.stem.2021.03.022. Epub 2021 Apr 28

Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion.

“Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion”
Saito Y, Desai RR, Muthuswamy SK
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. Volume 1869, Issue 2, 2018, Pages 103-116, ISSN 0304-419X, https://doi.org/10.1016/j.bbcan.2017.12.001

α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.

“α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism”
Escobar DJ, Desai R, Ishiyama N, Folmsbee SS, Novak MN, Flozak AS, Daugherty RL, Mo R, Nanavati D, Sarpal R, Leckband D, Ikura M, Tepass U, Gottardi CJ
J Cell Sci. 2015 Mar 15;128(6):1150-65. doi: 10.1242/jcs.163824. Epub 2015 Feb 4

Monomeric α-catenin links cadherin to the actin cytoskeleton

“Monomeric α-catenin links cadherin to the actin cytoskeleton”
Desai R, Sarpal R, Ishiyama N, Pellikka M, Ikura M, Tepass U
Nat Cell Biol. 2013 Mar;15(3):261-73. doi: 10.1038/ncb2685. Epub 2013 Feb 17

Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function

“Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function”
Sarpal R, Pellikka M, Patel RR, Hui FY, Godt D, Tepass U
J Cell Sci. 2012 Jan 1;125(Pt 1):233-45. doi: 10.1242/jcs.096644. Epub 2012 Jan 20

A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae.

“A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae
Novarina D, Desai R, Vaisica JA, Ou J, Bellaoui M, Brown GW, Chang M
G3 (Bethesda). 2020 Jun 1;10(6):1853-1867. doi: 10.1534/g3.120.401137

“Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae
Zhang C, Roberts TM, Yang J, Desai R, Brown GW
DNA Repair. 2006 Mar 7;5(3):336-46

“RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex”
Chang M, Bellaoui M, Zhang C, Desai R, Morozov P, Delgado-Cruzata L, Rothstein R, Freyer GA, Boone C, Brown GW
EMBO J. 2005 Jun 1;24(11):2024-33

 
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