Our long-term goal is to investigate and understand the key issue of neural control of movement: how different cellular, network and systems neural mechanisms are integrated across multiple levels of organization to produce motor behavior and to adapt this behavior to various external and internal conditions.

Investigations of neural circuits in the brainstem and spinal cord involved in neural control of locomotion and breathing provide a unique and attractive opportunity to develop and investigate comprehensive computational models that can bring into a uniform framework the existing experimental data and current hypotheses related to different levels of systems organization and behavior.

Our modeling studies are performed in close interactive collaboration with multiple leading experimental laboratories located in different universities, states and countries.