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Ying Jin

Ying Jin, PhD

Research Assistant Professor


Department: Neurobiology & Anatomy

Education

  • PhD - University of Hong Kong, Pok Fu Lam

Dr. Jin is a research assistant professor in the Department of Neurobiology & Anatomy at Drexel University College of Medicine.

 

Research

Dr. Ying Jin completed postdoctoral training at the University of Arkansas for Medical Sciences and the University of Kentucky.

Her research is focused on spinal cord injury, using multiple approaches to protect an injured spinal cord, reduce scar formation, and promote axonal regeneration and functional recovery. She is currently working on a combination stem cell transplanation and gene therapy treatment to bridge the lesion cavity, reduce glial scarring,and promote and guide axonal growth after a spinal cord injury, especially in the chronic stages of the injury.

Publications

"Directing dopaminergic fiber growth along a preformed molecular pathway from embryonic ventral mesencephalon transplants in the rat brain"
Jin Y, Zhang C, Ziemba KS, Goldstein GA, Sullivan PG and Smith GM
J. Neurosci Res., 89(5):619-27. PMID: 21337366 (2011).

"Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury"
Jin Y, Neuhuber B, Singh A, Bouyer J, Lepore A, Bonner J, Himes T, Campanelli JT, Fischer I
Journal of Neurotrauma. PMID: 21222572 (2011).

"Chondroitinase activity can be transduced by lentiviral vector in vitro and in vivo"
Jin Y, Ketschek A, Jiang ZL, Smith GM, Fischer I
J Neurosci Methods (in press, 2011).

"Targeting axon growth from neuronal transplantation in the adult central nervous system along preformed guidance pathways"
Ziemba KS, Chaudhry N, Rabchevshy AG, Jin Y, Smith GM
J. Neurosci. 28, 340-348. PMID: 18184776 (2008).

"Axon growth across a lesion site along a preformed guidance pathway in the brain"
Jin Y, Ziemba KS, Smith GM
Exp. Neurol., 210(2):521-30. PMID: 18261727 (2008).

"Evaluation of cellular organization and axonal regeneration through linear PLA foam implants in acute and chronic spinal cord injury"
Cai J, Ziemba KS, Smith GM, Jin Y
Journal of Biomedical Materials Research Part A. 83(2):512-520. PMID: 17503492 (2007).

"The mitochondrial uncoupling agent 2,4-Dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increase white matter sparing in the contused spinal cord"
Jin Y, McEwen ML, Nottingham SA, Maragos WF, Dragichevic NB, Sullivan PG, Springer JE
Journal of Neurotrauma 21(10): 1396-1404. PMID: 15672630 (2004).

"Overexpression of XIAP inhibits apoptotic cell death in an oligodendroglial cell line"
Jin Y, McEwen ML, Ghandour MS, Springer JE
Cellular and Molecular Neurobiology 24(6): 853-863. PMID: 15672685 (2004).

"Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury"
Jin Y, Fischer I, Tessler A, Houle JD
Experimental Neurology 177(1): 265-275. PMID: 12429228 (2002).

"Chronically injured supraspinal neurons exhibit only modest axonal dieback in response to cervical hemisection lesion"
Houle JD, Jin Y
Experimental Neurology 169 (1): 208-217. PMID: 11312573 (2001).

"Caspase-3 apoptotic signaling following injury to the central nervous system"
Springer JE, Nottingham SA, McEwen ML, Azbill RD, Jin Y
Clinical Chemistry Laboratory Medicine 39(4):299-307. PMID: 11388652 (2001).

"Expression of c-Jun in the lateral vestibular nucleus following spinal cord injury and peripheral nerve graft transplantation in adult rats"
Jin Y, Tay D, So K-F, Wu W
Journal of Neurocytology, 29 (2): 91-97. PMID: 11068337 (2000).

"Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons"
Jin Y, Tessler A, Fischer I, Houle JD
Journal of Neurorehabilitation and Neural Repair. 14: 311-317. PMID: 11402881 (2000).


Contact Information


Research Office

Department of Neurobiology & Anatomy
2900 W. Queen Lane
Philadelphia, PA 19129
Phone: 215.991.8284
Fax: 215.843.9082