(See all Fred Krebs' publications in PubMed.)
"Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1"
Pirrone V, Passic S, Wigdahl B, and FC Krebs
Virol J, 9: 33, 2012.
"Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors"
McFadden K, Fletcher P, Rossi F, Kantharaju, Umashankara M, Pirrone V, Rajagopal S, Gopi H, Krebs FC, Martin-Garcia J, Shattock RJ, and I Chaiken
Antimicrob Agents Chemother, 56: 1073-1080, 2012.
"Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety"
Lozenski K, Ownbey R, Wigdahl B, Kish-Catalone T, and FC Krebs
BMC Pharmacology & Toxicology, 13: 9, 2012.
"Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid"
Kortagere S, Madani N, Mankowski MK, Schon A, Zentner I, Swaminathan G, Princiotto A, Anthony K, Oza A, Sierra LJ, Passic SR, Wang X, Jones DM, Stavale E, Krebs FC, Martin-Garcia J, Freire E, Ptak RG, Sodroski J, Cocklin S, and AB Smith III
J Virol, 86: 8472-8481, 2012.
"Infection by CXCR4-tropic human immunodeficiency virus type 1 Is inhibited by the cationic cell-penetrating peptide derived from HIV-1 Tat"
Keogan S, Passic S, and FC Krebs
Int J Pept, 2012: 349427, 2012.
"A nipple shield delivery system for oral drug delivery to breastfeeding infants: microbicide delivery to inactivate HIV"
Gerrard SE, Baniecki ML, Sokal DC, Morris MK, Urdaneta-Hartmann S, Krebs FC, Wigdahl B, Abrams BF, Hanson CV, Slater NK, and AD Edwards
Int J Pharm, 434: 224-234, 2012.
"The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1"
Pirrone V, Wigdahl B, and Krebs FC
Antiviral Research, 90(3): 168-182, 2011
"Cervicovaginal safety of the formulated, biguanide-based human immunodeficiency virus type 1 (HIV-1) inhibitor NB325 in a murine model"
Lozenski K, Kish-Catalone T, Pirrone V, Rando RF, Labib M, Wigdahl B, and FC Krebs
J Biomed Biotechnol, 2011: 941061, 2011.
"Persistent interactions between biguanide-based compound NB325 and CXCR4 result in prolonged inhibition of human immunodeficiency virus type 1 infection"
Thakkar N, Pirrone V, Passic S, Keogan S, Zhu W, Kholodovych V, Welsh W, Rando R, Labib M, Wigdahl B, and Krebs FC
Antimicrobial Agents and Chemotherapy, 54(5): 1965-1972, 2010
"A styrene-alt-maleic acid copolymer is an effective inhibitor of R5 and X4 human immunodeficiency virus type 1 infection"
Pirrone V, Passic S, Wigdahl B, Rando RF, Labib M, and Krebs FC
Journal of Biomedicine and Biotechnology, 2010548749, 2010
"Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1"
Passic SR, Ferguson ML, Catalone BJ, Kish-Catalone T, Kholodovych V, Zhu W, Welsh W, Rando R, Howett MK, Wigdahl B, Labib M, and Krebs FC
Biomedicine and Pharmacotherapy, 64(10): 723-732, 2010
"Specific interactions between the viral coreceptor CXCR4 and the biguanide-based compound NB325 mediate inhibition of human immunodeficiency virus type 1 infection"
Thakkar N, Pirrone V, Passic S, Zhu W, Kholodovych V, Welsh W, Rando RF, Labib ME, Wigdahl B, and Krebs FC
Antimicrobial Agents and Chemotherapy, 53(2): 631-638, 2009
"Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120"
Gopi H, Cocklin S, Pirrone V, McFadden K, Tuzer F, Zentner I, Ajith S, Baxter S, Jawanda N, Krebs FC, and Chaiken IM
Journal of Molecular Recognition, 22(2): 169-174, 2009
"Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1"
Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schon A, Klein JC, Freire E, Krebs FC, Smith AB, Sodroski J, and Chaiken I
Journal of Medicinal Chemistry, 51(9): 2638-2647, 2008
"In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories"
Beer BE, Doncel GF, Krebs FC, Shattock RJ, Fletcher PS, Buckheit RW, Jr., Watson K, Dezzutti CS, Cummins JE, Bromley E, Richardson-Harman N, Pallansch LA, Lackman-Smith C, Osterling C, Mankowski M, Miller SR, Catalone BJ, Welsh PA, Howett MK, Wigdahl B, Turpin JA, and Reichelderfer P
Antimicrobial Agents and Chemotherapy, 50(2): 713-723, 2006