Dr. David Breen presents paper at BioVis '12
October 31, 2012 — Dr. David Breen, associate professor of computer science, presented the paper "Epithelial Cell Reconstruction and Visualization of the Developing Drosophila Wing Imaginal Disc" at the 2nd IEEE Symposium on Biological Data Visualization held in Seattle, Wash., October 14-15, 2012.
The paper describes a set of techniques that produces detailed 3D models of the individual cells in an epithelium from a stack of confocal microscopy images. The techniques were first utilized to construct the individual epithelial cells of the wing imaginal discs of larval Drosophila melanogaster. This research was also presented as a poster at the EMBO Conference on Morphogenesis and Dynamics of Multicellular Systems held in Heidelberg, Germany, September 7-9, 2012. Co-authors of the paper include Dr. Thomas Widmann of the Center for Genomics and Oncological Research, Drexel CS PhD candidate Linge Bai, Dr. Frank Jülicher of the Max Planck Institute for the Physics of Complex Systems and Dr. Christian Dahmann of the Dresden University of Technology.
The images below present results from the reconstruction method where the wing disc's individual cells have been color-coded as a function of their lengths and volumes.