Selected Publications

Howett, M.K ., N.D. Christensen and J.W. Kreider. Tissue xenografts as a model
system for study of the pathogenesis of papillomaviruses. Clinics in Dermatology, 15:
229-236, 1997.

Howett, M.K ., E.B. Neely, N.D. Christensen, B. Wigdahl, F.C. Krebs, D. Malamud,
S.D. Patrick, P.A. Welsh, C.A. Reed, M.G. Ward, L.R. Budgeon and J.W. Kreider.
A broad spectrum microbicide with virucidal activity against sexually transmitted viruses.
Antimicrob. Agents Chemother., 43: 314-321, 1999.

Krebs, F. C., Miller, S. R., Malamud, D., Howett, M. K., and B. Wigdahl. Inactivation
of human immunodeficiency virus type 1 by nonoxynol-9 (N-9), C31G, or an alkyl
sulfate, sodium dodecyl sulfate (SDS). Antiviral Research, 43(3): 157-173, 1999.

Shier, M.K., E.B. Neely, M.G. Ward, M.E. Richards, E.C. Manders, C. Meyers and
M.K. Howett. Correlation of overexpression of transforming growth factor b 1
(TGF b 1) with the down-regulation of proliferation-inducing molecules in HPV-11
transformed human tissue xenografts. Anti-cancer Res., 19: 4969-4976, 1999.

Howett, M.K ., P.A. Welsh, L.R. Budgeon, M.G. Ward, E.B. Neely, S.D. Patrick,
J. Weisz and J.W. Kreider. Transformation of human vaginal xenografts by human
papillomavirus type 11: Prevention of infection with a microbicide from the alkyl
sulfate chemical family. Pathogenesis, 1: 265-276, 2000.

Cain, J.M. and M.K. Howett. Preventing cervical cancer. Science, 288: 1753-1754,
2000.

Krebs, F.C., S.R. Miller, B.J. Catalone, P.A. Welsh, D. Malamud, M.K. Howett and
B. Wigdahl. Sodium dodecyl sulfate (SDS) and C31G as microbicidal alternatives to
nonoxnol-9 (N-9): Comparative sensitivity of primary human vaginal keratinocytes.
Antimicrob. Agents Chemother., 44:1 954-1960, 2000.

Kish , T.M., L.R. Budgeon, P.A. Welsh and M.K. Howett. Immunological
characterization of human vaginal xenografts in immunocompromised mice: Potential
small animal model for infection by human immunodeficiency virus type-1.
Am. J. Pathol., 159: 2331-2345, 2001.

Schlosser, B.J. and M.K.Howett. Human papillomaviruses: Molecular aspects of the
viral life cycle and pathogenesis. In: Colposcopy Principles and Practice: An Integrated
Textbook and Atlas (B.S. Apgar et al., ed.), W.B. Saunders Publishing Co.,
Chapter 2, pp.23-39, 2002.

Kish , T.M., M.G. Ward, P.A. Welsh, L.R. Budgeon, B. Wigdahl and M.K. Howett.
HIV-1 type 1 infection in a small animal human vaginal xenograft model. Journal of
Acquired Immunodeficiency Syndrome, Vol. 34, Number 5, December, 2003.

Fang, L., M.G. Ward, P.A. Welsh, L.R. Budgeon, E.B. Neely and M. K. Howett.
Suppression of human papilllomavirus gene expression in vitro and in vivo by herpes
simplex virus type 2 infection. Virology, 314(1): p. 147-60, 2003.

Catalone, B.J., T.M. Kish-Catalone, L.R. Budgeon, E.R. Neely, P.A. Welsh, F.C. Krebs,
M.K.Howett and B. Wigdahl. Mouse model of cervicovaginal toxicity and inflammation
for the preclinical evaluation of topical vaginal microbicides. Antimicrobial Agents and
Chemotherapy, 48(5): p 1837-47, 2004.

Kish , T. M., Culp, T. D., Myers, R., Neely, E., Christenson, N. D., Leure duPree, A.,
and M. K. Howett. Disruption of human papillomavirus type 11 by the candidate
vaginal, sodium dodecyl sulfate. Antiviral Research, In revision, 2004.

Howett, M. K. , E.B. Neely, M.G. Ward, I. Winicov, L. Fang and D. Gershon. Inhibition
of bovine papillomavirus type 1 (BPV-1) transformation and human papillomavirus
type 11 (HPV-11) transcription by the anti-viral agent, Doxovir. In revision, 2004.

Fang, L., Meyers, C., Budgeon, L.R., Howett, M.K. Induction of productive human
papillomavirus type 11 life cycle in epithelial cells grown in organotypic raft cultures.
Submitted, 2005.

Urdaneta, S., Wigdahl, B., Neely, E.B., Berlin, C.M., Shengrund, C.L., Lin, H.M.,
Howett, M.K. Biochemical analysis of human milk treated with sodium dodecyl
sulfate (SDS), an alkyl sulfate microbicide that inactivates HIV-1. Journal of Human
Lactation 2005, in press.

Urdaneta, S., Wigdahl, B., Neely, E.B., Berlin, C.M., Shengrund, C.L., Lin, H.M.,
Howett, M.K. Inactivation of HIV-1 in breast milk by treatment with the alkyl sulfate
microbicide sodium dodecyl sulfate (SDS). Retrovirology 2005;2:28

S. Urdaneta Hartmann, B. Wigdahl, E.B. Neely, C.M. Berlin, C.L. Schengrund,
H.M. Lin and M.K. Howett. Biochemical Analysis of Breast Milk treated with Alkyl
Sulfate Microbicides to Inactivate HIV-1. J Hum Lact, 22(1): 61-74, 2006.

S. Urdaneta Hartmann, C.M. Berlin and M.K. Howett. Alternative Modified Infant
Feeding Practices to Prevent Postnatal Transmission of HIV-1 Through Human Milk:
Past, Present and Future. J Hum Lact, 22(1):75-88, 2006.